Introduction: At present, pediatric mortality rates remain high, often due to preventable and identifiable causes, therefore, the application of this scale is opportune, since its easy access and high precision to establish the risk of mortality favor the taking of therapeutic decisions.

Material and methods: An observational, descriptive, prospective and cross-sectional study was carried out in order to evaluate the predictive approach of the PRISM scale applied to patients admitted to the Pediatric Intensive Care Unit of the San Lorenzo De Los Mina Maternal and Child Hospital. January–April 2020. The universe consisted of 37 patients from 1 month to 14 years old, who were admitted to the Intensive Care Unit and met the inclusion criteria, to whom the PRISM scale was applied within the first 24 hours of income taking into account the most altered value of each variable in the table.

Results: 53% were male, 47% were younger than 1 year. The average length of stay in the unit was 4.05 days (SD± 5.35). Of the admissions, 36% corresponded to respiratory pathologies (Pneumonia and Bronchial Obstructive Syndrome in Infants). 34% course with septic shock as the main pathology associated with mortality, the highest percentage of deaths was in the group PRISM > 30 (100%), followed by PRISM 20-30 (68%), and PRISM <20 with a probability of mortality (p<0.05%). 59% of the patients died, predominantly male and infants <1 year old. The standardized mortality was 1.07.

Conclusions: An adequate discrimination and approach of the PRISM scale as a predictor of mortality was determined.