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Publicado: 02/25/2023

DOI: https://doi.org/10.58994/adopa.v1i1.3

Factores pronósticos en pacientes pediátricos con síndrome inflamatorio multisistémico asociado a COVID-19

Cómo citar

1.
Brito Cruz GM, Alcántara-Manzueta S. Factores pronósticos en pacientes pediátricos con síndrome inflamatorio multisistémico asociado a COVID-19. ADOPA. 2023;1(1):25-46. Disponible en: http://adopa.pediatriadominicana.org/index.php/adopa/article/view/3

Resumen

Introducción: la infección por COVID-19 puede dar indicios de cuándo podría convertirse en síndrome inflamatorio multisistémico.

Material y métodos: estudio descriptivo, observacional, de corte transversal, con el obje- tivo de analizar los factores pronósticos en pacientes pediátricos con síndrome inflamatorio multisistémico asociado a la COVID-19, Hospital Materno Infantil San Lorenzo, de Los Mina, julio-diciembre 2020.

Resultados: de 148 pacientes fueron captados 21 casos con síndrome inflamatorio multi- sistémico asociado a la COVID-19, (14.19 %). Edades comprendidas de seis meses a 16 años, los de 10-14 años con un 36.36 %. En el sexo masculino fue más prevalente con un 66.67 %. Procedentes de la zona urbana, 85.71 %. Extranjeros, 14.29 %. Antecedentes personales pato- lógicos: asma, diabetes mellitus tipo I, neumonía, mixtos de asma más tuberculosis; asma más neumonía, asma más diabetes, se tomó en cuenta antecedentes no patológico de consumo de sustancia tóxicas, el 9.52 % manifestó consumir hookah. Las manifestaciones clínicas principales en orden de frecuencia fueron fiebre, rash cutáneo, dificultad respiratoria, equi- mosis, petequias, tos y hematomas, evacuaciones líquidas y palidez y púrpura. Se tomaron en cuenta los laboratorios: Dimero-D, así como la ferritina, procalcitonina, proteína C reactiva y velocidad de sedimentación eritrocitaria, siendo elevado en todos los casos. La proporción de pacientes que fueron con traslado coordinado fueron 52.38 %; pacientes no coordinados desde otros centros de salud 19.05 %. Con relación a la condición de egreso la entidad cursa con una alta mortalidad.

Conclusiones: las manifestaciones clínicas se presentan como factores pronósticos, la edad, el sexo y los resultados de laboratorio nos indican valorar e identificar el SIM-COVID19, alertando además el riego de mortalidad.

Abstract

Introduction: The COVID-19 infection can give indications of when it could become a multisystem inflammatory syndrome.

Material and methods: Descriptive, observational, cross-sectional study with the aim of analyzing prognostic factors in pediatric patients with multisystem inflammatory syndrome associated with COVID-19, Hospital Materno Infantil San Lorenzo, de Los Mina, July-De- cember 2020.

Results: Of 148 patients, 21 cases with multisystem inflammatory syndrome associated with COVID-19 were captured (14.19%). Ages from six months to 16 years, those of 10-14 years with 36.36%. In the male sex it was more prevalent with 66.67%. 85.71% from the urban area. Foreig- ners’ 14.29%. Personal medical history asthma, type I diabetes mellitus, pneumonia, mixed asthma plus tuberculosis; asthma plus pneumonia, asthma plus diabetes, non-pathological history of toxic substance consumption was considered, 9.52% reported consuming hookah. The main clinical manifestations in order of frequency fever, skin rash; respiratory distress, ecchymosis, petechiae, cough and bruising, liquid stools, and pallor and purpura. The labo- ratories were considered: D-dimer, as well as ferritin, procalcitonin, reactivated protein and erythrocyte sedimentation rate, being high in all cases. The proportion of patients who went with coordinated transfer was 52.38%; uncoordinated patients from other health centers 19.05%. In relation to the discharge condition, the entity has a high mortality.

Conclusions: Clinical manifestations are presented as prognostic factors, age, sex, and laboratory results indicate us to assess and identify SIM-COVID19, also alerting the risk of mortality.

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