El sialoblastoma es un tumor poco frecuente de las glándulas salivales, raramente diagnosticado en la infancia, que se presenta generalmente en los primeros meses de vida. Este reporte describe un caso de sialoblastoma en un recién nacido de 18 días de edad, que presentó una masa en la región facial derecha, con un crecimiento progresivo. Tras la realización de un ultrasonido cervical, se identificó una adenopatía submaxilar derecha, lo que llevó a la decisión de realizar una sialoadenectomía submandibular derecha bajo anestesia general. La cirugía fue exitosa, y el informe patológico confirmó la presencia de un tumor compuesto mayormente por nidos de células basaloides. Aunque los sialoblastomas pueden presentar recurrencias locales o metástasis, el pronóstico para los casos diagnosticados y tratados tempranamente es generalmente favorable. Este caso subraya la importancia de un diagnóstico temprano y una intervención quirúrgica adecuada para mejorar los resultados en pacientes pediátricos.
Sialoblastoma is a rare tumor of the salivary glands, rarely diagnosed in infancy, usually presenting in the first months of life. This report describes a case of sialoblastoma in an 18-day-old newborn, who presented with a progressively growing mass in the right facial region. A cervical ultrasound identified a right submandibular adenopathy, leading to the decision to perform a right submandibular sialodenectomy under general anesthesia. The surgery was successful, and the pathology report confirmed the presence of a tumor composed mostly of basaloid cell nests. Although sialoblastomas may present local recurrences or metastases, the prognosis for cases diagnosed and treated early is generally favorable. This case underscores the importance of early diagnosis and appropriate surgical intervention to improve outcomes in pediatric patients.
Vawter GF, Tefft M. Congenital tumors of the parotid gland. ArchPathol. 1966; 82:242- 24.
Taylor GP. Congenital epithelial tumor of the parotidsialoblastoma. Pediatr Pathol. 1988;8:447 – 452
Ellis GL. What’s New in the AFIP Fascicle on Salivary Gland Tumors: A Few Highlights from the 4th Series Atlas. Head and Neck Pathology [Internet]. 2009 Jul 20 [cited 2025 Mar 3];3(3):225–30. Available from: https://link.springer.com/article/10.1007/s12105-009-0128-z
Fonseca I, Martins AG, Soares J. Epithelial salivary gland tumors of children and adolescents in southern Portugal: a clinicopathologic study of twenty-four cases. Oral Surg Oral Med Oral Pathol. 1991;72:696 - 701.
Kwak J, Kim E. Thyroid Imaging Reporting and Data System Ultrasound Lexicon. Ultrasound Med Biol [Internet]. 2019 [cited 2025 Mar 3];25(5):75–82. Available from: https://socpr.org.pe/wp-content/uploads/2024/06/rev-vol21-caso-1.pdf
PEERAYUT SITTHICHAIYAKUL, JULINTORN SOMRAN, NONGLUK OILMUNGMOOL, WORASAKWUTTIPONG S, NOPPADOL LARBCHAROENSUB. Sialoblastoma of the cheek: A case report and review of the literature. Molecular and Clinical Oncology [Internet]. 2016 Mar 30 [cited 2025 Mar 3];4(6):925–8. Available from: https://www.spandidos-publications.com/10.3892/mco.2016.840
Ersoz S, Turgutalp H, Cobanoglu U, Bektas D, Yaris N. Sialoblastoma in the parotid gland: A case report. Pediatrics International [Internet]. 2010 Aug [cited 2025 Mar 4];52(4):670–2. Available from: https://onlinelibrary.wiley.com/doi/10.1111/j.1442-200X.2010.03108.x
Dardick I, Daley TD, McComb RJ. Sialoblastoma in adults: distinction from adenoid cystic carcinoma. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology [Internet]. 2009 Nov 1 [cited 2025 Mar 4];109(1):109–16. Available from: https://www.oooojournal.net/article/S1079-2104(09)00533-2/abstract
M. Prigent, N. Teissier, M. Peuchmaur, M. El Maleh-Berges, P. Philippe-Chomette, Cardin P, et al. Sialoblastoma of salivary glands in children: Chemotherapy should be discussed as an alternative to mutilating surgery. International Journal of Pediatric Otorhinolaryngology [Internet]. 2010 Jun 8 [cited 2025 Mar 4];74(8):942–5. Available from: https://www.sciencedirect.com/science/article/abs/pii/S0165587610000480?via%3Dihub
Karaman E, Duman C, Cansız H, Yildiz I, Dervişoglu S, Ozdemir G. Sialoblastoma in cheek region: Report of a case. International Journal of Pediatric Otorhinolaryngology Extra [Internet]. 2010 Mar [cited 2025 Apr 14];5(2):47–9. Available from: https://www.sciencedirect.com/science/article/abs/pii/S1871404809000100